Noncovalent interactions, in particular the hydrogen bonds and nonspecific long-range electrostatic interactions are fundamental to biomolecular functions. A molecular understanding of the local electrostatic environment, ...

Hydrogen-bonding plays a fundamental role in the structure, function, and dynamics of various chemical and biological systems. Understanding the physical nature of interactions and the role of electrostatics in hydrogen-bonding ...

Electrostatic interactions in proteins play a crucial role in determining the structure–function relation in biomolecules. In recent years, fluorescent probes have been extensively employed to interrogate the polarity in ...