Noncovalent interactions are at the center of many biological and chemical processes. There has been a conscious effort in recent times to exploit these interactions in order to achieve specific targets. However, to fully ...

Natural products play a vital role in the development of new chemical entities for drug discovery. Nearly, 40% drugs are either natural products or derived from natural products. Hence, their potential contribution makes ...

The present thesis demonstrates a creative exploration of aryne as versatile building blocks to construct new C–C and C–heteroatom bonds for the synthesis of various scaffolds and complex natural products. Chapter 1 describes ...

Aging is an irreversible degenerative process characterized by a general decline in cellular metabolic activity accompanied with progressive deterioration of cellular components resulting in enhanced mortality. Although, ...